A new hypothesis suggests that schizophrenia is a developmental disorder, which involves epigenetics—that switching business. Our brain with its 100 billion neurons begins developing in utero but is not fully formed until age 25 or so. Brain development involves neurons migrating from their place of origin to their destination (neuron pruning is also involved). The trip is set in motion by a gene switching on. If there were a glitch in this switching mechanism, it would not become apparent until adolescence, when brain development goes into high gear, and also when schizophrenia commonly flares up. This new insight is promising, but it doesn’t quite capture Susanne’s case, since she was in her early 30s when the disaster arrived.
Thanks for the link, John.